After extraction of the tooth #31 with mesial root fracture and a buccal fistula (Fig.1 <) and debridement, cortical/cancellous (50/50) mineralized allograft (.5-1 mm) saturated with ~ .3 ml of .3 mg/ml of rhPDGF-BB (one component of GEM21S) is placed in the socket.  

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Xin Wei, DDS, PhD, MS 1st edition 03/12/2020, last revision 03/12/2020